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在发展中求生存，不断完善，以良好信誉和科学的管理促进企业迅速发展产品名称：Rabbit Anti-Zyxin antibody
反应: (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
免疫原：KLH conjugated synthetic peptide derived from human Zyxin
保存：-20℃
保质期：1年
产品名称：Anti-Zyxin antibody
Mouse Anti-Zyxin
别名：ESP2; HED2; ZYX; Zyxin2.
免疫原：KLH conjugated synthetic peptide derived from human Zyxin
保存：-20℃
保质期：1年
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
应用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保质期：1年
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
